Your skin's repair signals slow down with age — NATUDERMA™ GHK-CU³ Copper Peptide Serum is engineered to turn them back on.
NATUDERMA™ GHK-CU³ Copper Peptide Serum is an advanced facial treatment engineered to promote smoother, toned, and youthful-looking skin. Formulated with a tri-peptide complex (Copper Tripeptide-1, Palmitoyl Tripeptide-1, and Palmitoyl Tetrapeptide-7) alongside Hyaluronic Acid, this lightweight formula delivers deep hydration to leave skin feeling firmer, smoother, and visibly plumped.
Why NATUDERMA™ GHK-CU³ Works
Copper peptides are among the most studied actives in anti-aging skincare. GHK-Cu (Copper Tripeptide-1) signals the skin to produce more collagen and elastin, accelerates tissue repair, and neutralizes free radical damage. Paired with Methylene Blue — a next-generation antioxidant — this formula delivers a dual defense against premature aging while restoring skin's structural integrity.
Key Ingredients
Copper Tripeptide-1 (GHK-Cu)
The gold standard of peptide skincare. Stimulates collagen and elastin synthesis, supports skin regeneration, and helps reduce the appearance of fine lines and sagging.
Palmitoyl Tripeptide-1 & Palmitoyl Tetrapeptide-7
A clinically recognized peptide duo (Matrixyl® 3000 complex) that signals fibroblasts to rebuild the skin matrix — reducing wrinkle depth and improving skin tone over time.
Methylene Blue
A powerful antioxidant that fights oxidative stress at the cellular level, supports mitochondrial function, and encourages collagen and elastin production. Responsible for the serum's natural blue color — no artificial dyes.
Sodium Hyaluronate (Hyaluronic Acid)
Draws moisture deep into the skin layers for lasting hydration, leaving skin visibly plumped and supple.
Camellia Sinensis (Green Tea) Leaf Extract
Rich in polyphenols and EGCG — soothes inflammation, protects against UV-induced oxidative damage, and supports an even skin tone.
Citrus Aurantium Dulcis (Orange) Peel Extract
A natural source of Vitamin C precursors and bioflavonoids that brighten skin and support collagen stability.
Product Highlights
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Clean Formula: Paraben-Free | Phthalate-Free | Gluten-Free | No Animal Testing
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Made in USA | 12M Period-After-Opening (PAO)
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Net Volume: 1.0 FL. OZ. (30 mL)
Full Ingredients
Water (Aqua), Sodium Hyaluronate, Palmitoyl Tripeptide-1, Palmitoyl Tetrapeptide-7, Glycerin, Butylene Glycol, Carbomer, Polysorbate 20, Cocos Nucifera Oil, Copper Tripeptide-1, Simmondsia Chinensis Seed Oil, Citrus Aurantium Dulcis Peel Extract, Camellia Sinensis Leaf Extract, Methylene Blue, Phenoxyethanol.
How to Use
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Introduce Gradually: Start by applying 4–6 drops twice a week at night to clean face and neck.
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Apply Gently: Massage upward until fully absorbed.
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Build Frequency: Increase to daily use as tolerated.
⚠️ Important: Do not layer with Vitamin C, AHA/BHA exfoliants, or Retinol in the same routine.
Caution
For external use only. Avoid eye contact. Patch test prior to use; avoid if sensitive or allergic to any listed ingredients. Discontinue if irritation occurs. Keep out of reach of children.
Frequently Asked Questions
Can I use this serum with Retinol, Vitamin C, or AHA/BHA exfoliants?
No. Do not layer this serum with Retinol, Vitamin C, or AHA/BHA exfoliants in the same routine. Combining copper peptides with direct acids or Retinol can cause ingredient instability, reduced efficacy, or skin irritation.
How do I use copper peptides alongside my other actives?
Option A (Time of Day): Use Vitamin C in the morning (with SPF) and NATUDERMA™ GHK-CU³ at night. Skip Retinol on nights you use this serum.
Option B (Alternate Nights): Rotate — Retinol on Night 1, NATUDERMA™ GHK-CU³ on Night 2.
How quickly should I build up to daily use?
Start with 4–6 drops twice a week at night. As your skin adapts over 2–4 weeks, gradually increase to daily application.
Why is the serum blue?
The vibrant blue color is 100% natural — it comes directly from Copper Tripeptide-1 (GHK-Cu) and Methylene Blue. No artificial dyes or synthetic colorants are added.
What is Methylene Blue and why is it in this serum?
Methylene Blue is an advanced antioxidant that fights oxidative stress, supports cellular vitality, and encourages collagen and elastin synthesis. Combined with GHK-Cu, it forms a powerful anti-aging defense system.
Is this suitable for sensitive skin?
The formula is paraben-free, phthalate-free, and gluten-free. Because active peptides are concentrated, always perform a patch test before full application and discontinue if irritation develops.
