DMAE has gained much popularity in skin care due to its anti-aging benefits. DMAE is a great ally to fight against the visible signs of aging thanks to its tightening and firming action that also provides great hydration to the skin and improves spots, unifying skin tone.
DMAE is also credited with increasing phosphatidylcholine, a fatty acid (lipid) that is derived from choline. Phosphatidylcholine is believed to have an antioxidant effect that protects skin cells from free radical damage. This effect may be related to similar claims that DMAE improves skin cells' ability to retain water, a process that helps cells heal but can also lead to smoother skin.
What is DMAE?
DMAE is an analog of the B vitamin choline and is a precursor of acetylcholine. DMAE occurs naturally in the body, where it makes choline and acetylcholine. Although the role of acetylcholine as a neurotransmitter is well known, growing evidence points to acetylcholine as a ubiquitous cytokine-like molecule that regulates basic cellular processes such as proliferation, differentiation, locomotion, and secretion in a paracrine and autocrine fashion. Indeed, this modulatory role may contribute to the cutaneous activity of DMAE. The architect of skin firmness.
What studies support the benefits of DMAE?
In a clinical study performed on 2007, 3% DMAE facial gel applied daily for 16 weeks has been shown to be safe and efficacious in the mitigation of forehead lines and periorbital fine wrinkles, and in improving lip shape and fullness and the overall appearance of aging skin. These effects did not regress during a 2-week cessation of application. Beneficial trends were noted in the appearance of coarse wrinkles, under-eye dark circles, nasolabial folds, sagging neck skin, and neck firmness. The acute skin-firming effects of DMAE have been confirmed by quantitative measures of cutaneous tensile strength, the benefits of DMAE in dermatology include a potential anti-inflammatory effect and a documented increase in skin firmness with possible improvement in underlying facial muscle tone. (1)
The vacuolar cytopathology induced by concentrated organic amines may be the cellular basis of the antiwrinkle effect of DMAE. (2)
The studies of 2014 have confirmed all the skin benefit of DMAE, Mesotherapy by delivering DMAE and AA directly to target tissue has marked antiaging effects by promoting collagen synthesis and catabolism to remodel skin texture and improving the thickness of aging skin. (3)
Where can I find DMAE in its pure grade?
The BCN mesotherapy line offers us some mesotherapy serums, for topical use of cosmeceutical (mesoceutical) and sterile quality, among them we can get DMAE, in presentation of 10 ampoules of 5ml each. Very easy to apply, just clean and dry skin of the face and / or body, massage gently until completely absorbed.
Also, you can use: Meso Roller, Meso Pen, galvanic currents (iontophoresis, hydroelectrophoresis), radiofrequency, ultrasound (sonphoresis), IR thermotherapy (cataphoresis), electromagnetic waves (electroporation), cryoelectrophoresis and vacuotherapy. Not Injectable.
You can find product containing DMAE in the following links.:
Other products are: